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Natural – Holistic – Energy – Prosperity – MMS

MSM for Pets and livestock

MSM Sulfur is a essential nutrient that aids in maintaining health as well as providing treatment to the numerous ailments that pets can become afflicted with as they grow older.

Do you have a dog or cat that is getting older, and you’ve noticed he or she seems to be

  • getting slower?
  • Does your dog or cat seem to have trouble sitting down, getting up?
  • It is no surprise that a great many family pets suffer from arthritis joint pain, just as people do.
  • Joint Pain is generally the same in humans as in dogs and cats, only dogs and cats lack the ability to communicate their arthritis pain. So pet’s do what they can by being less playful, hiding away, becoming more aggressive or simply refusing to be as active as before. This is not your dogs and cats fault. Also the joints may have Lyme disease and need the water purifier drops also called MMS (Not to be confused with MSM)
  • Many times, older dogs and cats that have slowed down have degenerated cartilage in their joints, leading to arthritis joint pain that can be eased with  MSM Supplements.

MSM is the perfect solution for dogs, cats, and even horses with digestive disorders, arthritis, allergies, inflammation, skin/coat and eye problems.

Signs of Arthritis in Cats and Dogs:

  • Slow in getting up
  • Decline in energy
  • Whining
  • Hiding or sleeping too much
  • Lameness
  • Stiffness of back and hips
  • Sensitivity to touch or handling
  • Difficulty in climbing stairs or steps

Horses

I saw a BIG difference in the horses receiving MSM. They are doing better overall and have fewer medical problems. The most impressive thing is how much better they are training. Submitted by Mike Fisher, experienced standardbred trainer

Supplementing your pets diet with additional MSM sulfur ensures the body’s ability to heal itself. Pets who suffer from arthritis often benefit greatly from Cardinal quality Pure MSM supplements. Several studies have shown, that supplementation of MSM, significantly reduced joint degeneration and inflammation. Micro Pro fine powder is manufactured in the USA and is the best selling brand of MSM World Wide.

  • Two of the race horses were near their lifetime records in their second starts after being on 20 grams of MSM for just less than a month. Submitted by Dr. Ronald Reigel

MSM takes out the pain and inflammation, permits the muscles to heal and prevents them from becoming sore.

Veterinairians have been using MSM/DMSO for over 35 years to relieve dog and cat chronic pain and inflammation from arthritis or hip dysplasia in Animals. MSM (DMSO) Sulfur Powder Supplements are Essential to your Dog or Cat’s Health

  • I use MSM as a natural anti-inflammatory product for the animals. There is nothing that works as well. Submitted by Ann Grell, JAG Ranch

Does your dog suffer from arthritis pain and inflammation? Arthritis and joint problems are very common in aging dogs. The most common symptoms of arthritis and joint disease in dogs include stiffness, limping or favoring a limb (particularly after sleep or resting), inability to rise, reluctance to jump or even climb stairs, and sometimes other noticeable pain.

Arthritis or joint inflammation occurs in dogs most commonly when there are degenerative changes in malformed joints, such as with hip Dysplasia. Arthritis can also result from trauma, infection or an immune-mediated disease such as rheumatoid arthritis.

Trying to find pain relief for dogs with arthritis can be difficult while the majority of veterinarians will prescribe aspirin or prescription medications. With these medications, there is always the risk of side effects. The most common side effects for these medications are gastrointestinal problems, such as hemorrhaging or even ulcers. There are no bad side effects with your pet taking natural MSM.

MSM for Horses: Why just keep yourself healthy? Horses just like any other animal or human can benefit from the use of MSM supplements. The best place to start is their diet, for it is the main foundation of their natural health care. Scientists say that mineral deficiency subjects our animals to more diseases, along with aging and sickness.

  • John Metcalf, DVM, a well-known equine practitioner, started his evaluation of MSM to treat a variety of illnesses in horses, including chronic muscle soreness, epiphysis’s, acute laminitis, pleuritis, recurring digestive tract disorder and arthritis.
  • MSM powder and/or crystal-flakes for horses is now widely acclaimed by veterinarians and horsemen for its contribution to equine health care and horse ailments in the equestrian world.
  • MSM for horses is the food supplement known and used by many horsemen and veterinarians throughout the horse and pet industry all over the world.
  • MSM for horses and pets has helped ease a number of horse and pet ailments. MSM  was discover by Dr. Robert Herschler. MSM for horses is a 100% pure licensed dietary supplement approved by veterinarians.

Cats are even more at risk for side effects because their unique physiology doesn’t always respond well to the prescription medicines that benefit dogs and humans. There are no medicines licensed for use in cats to treat chronic pain.

Most pain pills – NSAIDs such as aspirin, Tylenol, Aleve and Ibuprofen are toxic to cats as the feline liver is unable to break down and process the chemicals. Consequently, cats cannot rid themselves of the toxic byproducts of these chemicals.

Danger to cats: A single dose of aspirin or another NSAID can be fatal to a cat.

Want to keep your Pets healthy and active? By adding MSM Supplements to your pet’s daily diet, you will see a noticeable difference in their daily activity.

MSM Sulfur Powder Supplements Recommended Dosage: Vets have recommend mixing 500 mg (1/8th teaspoon) MSM powder Powder per 10 lbs. of body weight in your pet’s daily water supply.

Please consult your veterinarian for your pets recommended msm dosage requirement for specific health conditions.

Adding MSM nutritional sulfur to your pets diet on a daily basis can help with all of these health conditions, safely and without the risk of side effects or drug interactions.

Did you know that the as seen on TV Advertisement promoting the amazing ” Dr. Franks Pain relief Pet Spray for Dogs and Cats “, lists one of their main active ingredients as MSM Sulfur” ?

Arthritis prescription medications for dogs are costly and can come with serious side effects. MSM has no side affects.

DAILY MSM DOSAGE

Animal or Pet Weight – Dosage
Cats – 250 mg. or 1/10th Tsp. or 1/2 cc
Dogs up to 30 lbs. – 500 mg. or 1/5 tsp. or 1 cc
Dogs 31 to 60 lbs. – 1000 mg. or 2/5 tsp. or 2 cc’s
Dogs 60 + lbs. – 1500 mg. or 3/5 tsp. or 3 cc’s
Goats & Sheep 125 to 250 lbs. – 2500 mg. or 1 tsp. or 5 cc’s
Horses – 1 ounce daily or 1/2 ounce twice daily as needed

The most effective Natural Remedies available for conditions such as arthritis and hip dysplasia in animals will include MSM sulfur and also Glucosamine/Chondroitin supplements.

At last, a highly effective, pleasant tasting, non-prescription oral spray with MSM Sulfur, that stops Pain SAFELY. Just drop you mixture into your pets water dish once or twice a day to significantly reduce chronic joint and muscle pain and stiffness whether mild or severe, it stops the pain anywhere and from any cause.
If your Pet has joint or muscle pain try this product today!
You can now stop the pain without worrying about SAFETY.

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MSM – Eight Ounce Package of Powder

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Methylsulfonylmethane (MSM), also known as dimethyl sulfone, is an organosulfur compound with the formula (CH3)2SO2.

In more common terms, MSM is a common sulfur element found in many foods. Time and processing diminish the quality of MSM in foods, and in our fast, highly processed world this basic element can become deficient in our diets.

Clinical evidence for MSM usefulness is limited to animal studies and four published clinical studies in humans with the most positive a study in the treatment of osteoarthritis. As reported by Wikipedia:

Osteoarthritis: “After several reports that MSM helped arthritis in animal models, a double-blind, placebo-controlled study suggested that 1500 mg per day MSM (alone or in combination with glucosamine sulfate) was helpful in relieving symptoms of knee osteoarthritis”.

MSM is organic sulfur.  MSM also stands for “Methyl Sulfonyl Methane.”

On this web site you will find several pages about MSM.  You will also find the lowest prices of any of hundreds of web sites offering MSM.  In fact, you can buy wholesale here if you are interested in bulk supplies.

This website serves as a resource for consumers, researchers, medical practitioners and media who want to learn about the science and evidence for MSM.

MSM, methylsulfonylmethane (METH-?l-sul-FON-il-METH-ane) provides sulfur, a vital building block of joints, cartilage, skin, hair and nails, and methyl groups, which support many vital biochemical processes in the body, including energy production. MSM is a naturally-occurring nutrient found in small amounts of many foods.

As a dietary supplement, MSM is synthesized. When made correctly, it is identical to that found in nature. MSM can be taken alone or in combination with other joint health supplements, such as glucosamine and chondroitin.

From experience we have found MSM to be less toxic than water and also you’ll find it is also far less expensive than many nutritional products which do far less good.

WE think of MSM as primarily a cleansing agent, but it is almost more famous for its ability to relieve the pains of arthritis, and reduce scar tissue, etc.

How to take MSM

The cheapest way is in bulk.  You can take it by the teaspoonful — one heaping teaspoon is about 5 grams and some people would encourage you to start small, but build up to about 20 grams per day.

With capsules, I recommend you start with a few, but do not hesitate to get up to 20 or more capsules per day.  You can pull a capsule apart to put the contents into any beverage or to use in other ways.
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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MSM – 8 ounce package

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MSM 8 ounce package is a good deal – MSM … Natural Sulfur Compound Found In All Living Things. Works Wonders For Arthritis, Builds healthy Flexible Cells, and Used For Overall Body Balance.

MSM belongs to a family of compounds that are abundant in the food chains of terrestrial and ocean life. This sulfur-containing nutrient is the stable end product of the methyl-S-methane series of compounds that provide bioavailable sulfur to as many as 85% of all living organisms. These compounds—principally dimethyl sulfide (DMS)—are among the Earth’s few primary sources for sulfur.

The sulfur cycle begins in the ocean, where algae and phytoplankton release sulfur compounds, called tertiary dimethylsulfonium salts. These salts are transformed to DMS, a highly volatile compound. Oceanic DMS is the major natural source of sulfur to the atmosphere and contributes both to the tropospheric sulfur burden and to particle formation and growth in the atmosphere.

MSM Safety

MSM has been shown to be safe by several studies. In thirty years there have been no reported adverse events to MSM. It’s also important to note that sulfa allergies do not apply to MSM.

Some Clinical studies of MMS

Human Clinical Trials
Kim LS, Axelrod LJ, Howard P, Buratovich N, Waters RF. Efficacy of methylsulfonyl-methane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis and Cartilage 2006;14:286-94.
Southwest College Research Institute, Southwest College of Naturopathic Medicine & Health Sciences, Tempe, AZ, USA. [Abstract on PubMed]

In 2004, Kim et al conducted a randomized, double-blind, placebo-controlled clinical trial to evaluate the effects of distilled MSM on mild to moderate osteoarthritis of the knee. Participants received 3,000 mg twice daily of either placebo or MSM (OptiMSM, Bergstrom Nutrition, Vancouver, WA)) for 12 weeks. Patients were evaluated using standardized clinical efficacy scales as well as for several secondary endpoints, adverse events, and clinical laboratory markers. Compared to placebo, those taking MSM had statistically significant reductions in pain and in difficulty performing activities of daily living. Statistically significant reductions in serum homocysteine (a risk factor for cardiovascular disease) and urinary malondialdehyde (a marker of oxidative stress) were also observed. There were no significant adverse events in the study.

Engelke UF, Tangerman A, Willemsen MA, et al. Dimethyl sulfone [MSM] in human cerebrospinal fluid and blood plasma confirmed by one-dimensional (1)H and two-dimensional (1)H-(13)C NMR. NMR Bio Med 2005;18:33l-6.
Radboud University Nijmegen Medical Centre, Laboratory of Pediatrics and Neurology, L-6500 HB Nijmegen, The Netherlands. [Abstract on PubMed]

(1)H-NMR spectroscopy at 500 MHz was used to confirm that a previously unidentified singlet resonance at 3.14 ppm in the spectra of cerebrospinal fluid and plasma samples corresponds to dimethyl sulfone (DMSO(2)). A triple resonance inverse cryogenic NMR probe, with pre-amplifier and the RF-coils cooled to low temperature, was used to obtain an (1)H-(13)C HSQC spectrum of CSF containing 8 microM (753 ng/ml) DMSO(2). The (1)H-(13)C correlation signal for DMSO(2) was assigned by comparison with the spectrum from an authentic reference sample. In plasma and CSF from healthy controls, the concentration of DMSO(2) ranged between 0 and 25 micromol/l. The concentration of DMSO(2) in plasma from three of four patients with severe methionine adenosyltransferase I/III (MAT I/III) deficiency was about twice the maximum observed for controls. Thus, DMSO(2) occurs as a regular metabolite at low micromolar concentrations in cerebrospinal fluid and plasma. It derives from dietary sources, from intestinal bacterial metabolism and from human endogenous methanethiol metabolism. Copyright (c) 2005 John Wiley & Sons, Ltd.

Barrager E, Veltmann JR, Schauss AG, Schiller RN. A multi-centered, open label trial on the safety and efficacy of methylsulfonylmethane in the treatment of seasonal allergic rhinitis. J Altern Complement Med 2002;8:167-74.

In a open-label study of 55 patients with seasonal allergic rhinitis (SAR; hayfever), MSM at 2600mg/day significantly reduced upper and total respiratory symptoms within 7 days; lower respiratory symptoms were significantly improved from baseline by week 3. No significant changes were observed in plasma IgE or histamine levels. Few side effects were associated with the use of MSM and no patient dropped out of the study due to adverse reactions. Energy levels increased significantly by day 14. The results suggest that MSM may be an efficacious in reducing symptoms associated with SAR.

Blum JM, Blum RI. The effect of methylsulfonylmethane (MSM) in the control of snoring. Integrative Medicine 2004;3(6)24-30.
Childs SJ. Dimethyl sulfone (DMSO2) in the treatment of interstitial cystitis. Urol Clin North Am 1994;21:85-8.

Dr. Childs presents six case studies on the use of intravesicular MSM for interstitial cystitis in patients who were refractory to previous therapy.

Lawrence RM. Methylsulfonylmethane (M.S.M.) A double-blind study of its use in degenerative arthritis. Int J Anti-Aging Med 1998;1(1):50 [abstract].

In this abstract, Lawrence presented data on a “preliminary study” in which patients suffering from degenerative arthritis were treated with either 2,250 mg per day of MSM (Adaptin, no manufacturer specified) or placebo for an unspecified length of time. Sixteen patients were reportedly enrolled in the study. Eight received MSM and six received placebo. The author does not indicate what treatment, if any, was administered to the two remaining patients. Lawrence reported “a better than 80 percent control of pain within six weeks of beginning the study.” The title of the abstract indicates that a double-blind protocol was followed.

Usha PR, Naidu MUR. Randomised, double-blind, parallel, placebo-controlled study of oral glucosamine, methylsulfonylmethane and their combination in osteoarthritis. Clin Drug Invest 2004; 24:353-63.

Randomized, double-blind trial comparing MSM, glucosamine, both, or placebo for osteoarthritis of the knee. Approximately 30 patients per group. Dose was 1,500 mg per day for 12 weeks. The efficacy parameters studied were the pain index, the swelling index, visual analogue scale pain intensity, 15m walking time, the Lequesne index, and consumption of rescue medicine. There were statistically significant decreases in pain with Glu and with MSM respectively. The combination treatment resulted in a more significant decrease in the mean pain index than either treatment alone. Conclusion: Glu, MSM and their combination produced an analgesic and anti-inflammatory effect in osteoarthritis. Combination therapy showed better efficacy in reducing pain and swelling and in improving the functional ability of joints than the individual agents.

Vidyasagar S, Mukhyaprana P, Shashikiran U,et al. Efficacy and Tolerability of glucosamine chondroitin sulphate – methyl sulfonyl methane (MSM) in osteoarthritis of knee in Indian patients. Iran J Pharmacol Ther 2004;3:61-5.
Isolation; presence in nature, in animals and humans
Pearson TW, Dawson HJ, Lackey HB. Natural occurring levels of dimethyl sulfoxide in selected fruits, vegetables, grains and beverages. J Agric Food Chem 1981; 29:1019-21.

Performed at Crown-Zellerbach, this study documents the presence of MSM (DMSO2; Me2SO2) in asparagus, alfalfa, beets, cabbage, corn, cucumber, oats, swiss chard, tomatoes, apples, raspberry, beer, coffee, milk and tea.

Pfiffner JJ, North HB. Dimethyl sulfone: A constituent of the adrenal gland. J Biol Chem 1940;134:781-2.

From the research labs of Parke-Davis, one of the earliest isolations of dimethyl sulfone (1940). Originally isolated from cattle blood, this study found MSM in fresh beef glands.

Williams KIH, Burstein SH, Layne DS. Dimethyl sulfone: isolation from cows’ milk. Proc Soc Exp Biol Med 1966;122:865-6.

Supported in part by the National Institute of Arthritis and Metabolic Diseases and performed at the Worcester Foundation for Experimental Biology, this study isolated MSM from cow’s milk and noted that urinary excretion of MSM approximated 5-10mg/24 hours in humans.

Williams KIH, Burstein SH, Layne DS. Dimethyl Sulfone:  Isolation from human urine. Arch Biochem Biophys 1966;113:251-2.

MSM is isolated in human urine. In samples from 4 women and 4 men, the rate of excretion varied from 4mg to 11mg. The authors speculate that the MSM excreted may be derived from dietary sources or a product of the metabolism of sulfur containing amino acids.

Williams KIH, Burstein SH, Layne. Metabolism of dimethyl sulfide, dimethyl sulfoxide, and dimethyl sulfone in the rabbit. Arch Biochem Biophys 1966;117:84-7.
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Animal Studies
David Amiel, PhD; Robert M Healey, BS, MBA and Yasushi Oshima, MD, PhD, Assessment of methylsulfonylmethane (MSM) on the development of osteoarthritis (OA): An animal study FASEB J. 2008 22:1094.3.

This study examined the effects of ultra pure methylsulfonylmethane (OptiMSM) on osteoarthritis of the knee. A prior study showed that while OptiMSM is clinically effective, the mechanism remained enigmatic. In this study, the right knee ACL was transected (ACLT) in mature NZW rabbits (n=10) (2). Five weeks after ACLT an MSM constant delivery system to the joint was created by implanting an Alzet osmotic pump. Controls received no other treatment. Animals were sacrificed 9 wks postop, and OA grading of the femoral surface was performed: Grade-I (G-1): intact surface; Grade-II (G-II): minimal fibrillation; Grade-III (G-III): overt fibrillation; and Grade-IV (G-IV): erosion of articular cartilage surface (2). Results showed 2 G-III and 1 G-IV (avg 3.3) in control. The MSM-treated group showed 1 G-I, 3 G-II, 1 G-III, and 2 G-IV (avg 2.6). Expression of type II collagen and aggrecan showed no difference between control and MSM, yet expression of TNF-a in both cartilage and synovial tissue was decreased by MSM (p<0.01). MSM preserved the articular cartilage surface during OA development and reduced inflammation (i.e. TNF-a) in both cartilage and synovium.

Robert A DiSilvestro, David J DiSilvestro, and Daniel J DiSilvestro, Methylsulfonylmethane (MSM) Intake in Mice Produces Elevated Liver Glutathione and Partially Protects Against Carbon Tetrachloride-Induced Liver Injury FASEB J. 2008 22:445.8.

MSM’s antioxidant actions have been proposed based mostly on indirect evidence. For example, antioxidant actions in vivo of a related compound, DMSO, may be produced by MSM formed in vivo from DMSO. Thus, a study was done in mice to determine whether oral intake of OptiMSM could affect tissue levels of an internal sulfur-containing antioxidant, glutathione, and resistance to chemically-induced oxidant stress. MSM administration (5 weeks, 80 mg/100 ml drinking water) produced a statistically significant increase in liver glutathione (mean increase of 78%). A similar effect was not seen in lung or skeletal muscle. In addition, MSM partially inhibited liver injury after injection of carbon tetrachloride, which induces liver oxidant stress (injury evaluation based on blood indexes of hepatic injury). These results indicate the need for further testing for MSM antioxidant actions in vivo, and to explore the mechanism of elevated glutathione.

Magnuson, B.A., Appleton, J., Ryan, B., Matulka, R.A., Oral Developmental Toxicity Study of Methylsulfonylmethane in Rats, Food and Chemical Toxicology (2006), doi: 10.1016/j.fct.2006.12.003

The objective of these studies was to determine the developmental toxicity potential of MSM when administered orally to pregnant rats during the period of major organogenesis and histogenesis. In a preliminary dose-finding study, distilled MSM microprill (i.e., microspherical pellets of MSM) was administered by oral gavage at dose levels of 0 (vehicle control), 50, 250, 500, and 1000 mg/kg/day to 8-9 sperm-positive female Sprague-Dawley rats/group/day on gestation days 6 through 20. No evidence of maternal or fetal toxicity was observed. For the definitive developmental study, four groups of 24-25 timed-bred primiparous female rats were administered 0, 50, 500, or 1000 mg MSM/kg/day via gavage on gestation days 6 through 20. Maternal feed consumption, body weight, body weight gain, uterus weight and corrected body weight/body weight gain were unaffected by treatment. No evidence of maternal toxicity, and no significant differences in litter viability, litter size, or litter body weight were detected. Fetal evaluations failed to show any biologically significant increase in the incidence of anomalies in the MSM treated groups, and no malformations were seen in any of the fetuses. No evidence of fetal mortality, alterations to growth, or structural alterations were observed in the fetuses of dams administered 50 to 1000 mg/kg/day. Therefore, under the conditions of this study, the no-observed-adverse-effect level (NOAEL) for maternal and developmental toxicity was 1000 mg/kg/day.

Magnuson, B.A., Appleton, J., Ames, B.A., Pharmacokinetics and Distribution of [35S]Methylsulfonylmethane following Oral Administration to Rats, Journal of Agricultural and Food Chemistry (2006)

The objective of this study was to evaluate the pharmacokinetic profile and distribution of radiolabeled MSM in rats. Male Sprague-Dawley rats were administered a single oral dose of [35S]MSM (500 mg/kg), and blood levels of radioactivity were determined at different time points for up to 48 h. Tissue levels of radioactivity at 48 and 120 h and urine and fecal radioactivity levels were measured at different time points for up to 120 h following [35S]MSM administration to rats. Oral [35S]MSM was rapidly and efficiently absorbed with a mean tmax of 2.1 h, Cmax of 622 µg equiv/mL, and AUC0-inf of 15124 h.µg equiv/mL. The t1/2 was 12.2 h. Soft tissue distribution of radioactivity indicated a fairly homogeneous distribution throughout the body with relatively lower concentrations in skin and bone. Approximately 85.8% of the dose was recovered in the urine after 120 h, whereas only 3% was found in the feces. No quantifiable levels of radioactivity were found in any tissues after 120 h, indicating complete elimination of [35S]MSM. The results of this study suggest that [35S]MSM is rapidly absorbed, well distributed, and completely excreted from the body.

Richmond VL. Incorporation of methylsulfonylmethane sulfur into guinea pig serum proteins. Life Sci 1986;39:263-8.
Wang M-Y, Anderson G, Nowicki D. Preventive effect of methylsulfonylmethane (MSM) at the induction stage of mammary carcinogenesis induced by DMBA in female SD rats. Proc Am Assoc Cancer Res 2003; 44(8):787 [Abstract #3445].
Wang M-Y, Anderson GL, Nowicki D. Synergistic effect of Tahitian Noni Juice (TNJ) and methylsulfonylmethane (MSM) on mammary breast cancer prevention at the initiation stage of chemical carcinogenesis induced by DMBA in female Sprague-Dawley (SD) rats. Cancer Epidemiol Biomarkers Prev 2003;12:1354S.
Carlson, RP [study director]. Bergstrom Nutrition rat carrageenan air pouch model No. 1. White Eagle Toxicology Laboratories [Unpublished: data on file]. (Sponsored by Bergstrom Nutrition).

Anti-inflammatory actions of MSM observed in an experimental rat study in 2001. MSM compared to indomethacin in a rat carrageenan air pouch model. The objective of the study was to determine whether MSM inhibited leukocyte influx and edema in an acute inflammation model. MSM was administered orally (300 or 1,000 mg/kg for three days) to male CD Charles River rats, in which inflammation was produced with injections of carrageenan.  Oral MSM at 1,000mg/kg, administered for two days prior and up to two hours prior to carrageenan injections inhibited the total number of leukocytes migrating into the pouch at four hours by 26%. The 300mg/kg dose inhibited leukocyte infiltration by 18%. These results did not reach statistical significance, possibly due to the small number of animals studied, or because the anti-inflammatory effects of MSM are more likely to be demonstrated in a chronic inflammation model.

Gerhards E, Gibian H. The metabolism of dimethyl sulfoxide and its metabolic effects in man and animals. Ann N Y Acad Sci 1967;141:65-76.

Metabolism of DMSO, including its oxidation to MSM, in the human. Key factoid: 15% of ingested DMSO is rapidly oxidized to DMSO2 (MSM) in vivo, by hepatic microsomes in the presence of NADPH2 and molecular oxygen.

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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MSM – 16 Ounce package

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MSM 16 Ounce package. This technology ensures the highest quality of MSM on the market to-day, entirely free of any contaminants. The fine crystal powder form of MSM is sometimes preferred by people that like to dissolve the powder in a juice or in water.  Since the crystals are extremely fine, they dissolve quickly.

Here are some Questions and Answers

Few people are sulfur-deficient? Does MSM help?
A:
Most people derive all the sulfur they need from their diet, from the sulfur-containing amino acids cysteine and methionine, which are abundant in animal-derived foods such as meat, eggs, milk and other dairy products.  MSM is not needed to correct sulfur deficiency; it is useful for its own beneficial effects. Theoretically, if someone were deficient in sulfur, MSM could be a reasonably good source.

Does MSM have any proven effects on insulin, blood sugar, blood pressure, or peptic ulcer?
A:
No. Sulfur is a component of many amino acids and hormones, and is required for the production of many more. But just because sulfur is required to produce insulin, it is not correct to believe that taking sulfur as a supplement (e.g., in MSM) would have any effect on the body’s production or secretion of insulin. The regulatory pathways for blood sugar metabolism are far more complex than that.

What are the benefits of MSM over non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen?
A:
MSM is an effective anti-inflammatory agent. Unlike NSAIDs, however, it does not bad side effects such as causing gastritis or inhibit cartilage synthesis.

Can patients with allergies to sulfa drugs still take MSM?
A:
Many patients with allergies to sulfa drugs can take MSM. MSM contains no sulfonamides, and these allergies are not necessarily transferable to all sulfur-containing substances. However, patients with sulfonamide allergies also tend to have other medication allergies as well.

Is MSM safe for pregnant women and/or children?
A:
There are no known reasons why pregnant women and children could not take MSM. However, its safety for these groups has not been definitively proven. As with most nutritional supplements, MSM should not be taken by pregnant women or children unless prescribed by a qualified doctor. Research is currently underway to determine the safety of MSM for these groups of people.

Does MSM have any proven effects on insulin, blood sugar, blood pressure, or peptic ulcer?
A:
No. Sulfur is a component of many amino acids and hormones, and is required for the production of many more. But just because sulfur is required to produce insulin, it is not correct to believe that taking sulfur as a supplement (e.g., in MSM) would have any effect on the body’s production or secretion of insulin. The regulatory pathways for blood sugar metabolism are far more complex than that. These FAQ’s are from http://www.msmguide.com/msm-practitioner/faq/

How is MSM made? MSM is made from DMSO (Dimethyl Sulfoxide), and DMSO is made by processing the waste product (trees) of paper making (“pulp and paper industry”)– it is NEVER made by simply processing trees or any other form of plant life (no matter what you might read in some less informed Internet sources), for the sole purpose of extracting DMSO. It COULD be, just as sea water could be used for the sole purpose of extracting gold, but this is totally impractical.

In paper making — DMSO is extracted from the waste product of paper making — and it is the PAPER MAKING that allows the whole process to be practical. As paper is made, the paper is made of the fibers of wood. But, as trees grow, the fibers of wood are stuck together, in the living tree, by a substance called “lignin.” Lignin is like a glue that holds the fibers together. The wood could not be made into paper if all the fibers are still stuck together — so in paper making it must include some process by which the lignin is removed, allowing the wood fibers to be managed into flat paper, etc.

Lignin is removed with something called “pulping chemicals.” These chemicals are sodium sulfite (the majority), sodium sulfide and sodium carbonate). When these chemicals are soaked in a vat with wood chips, the lignin dissolves and the wood fibers can then be removed from the mass. Generally about 50% of the stuff in the vat would be the wood fibers, ready for making into paper, and 50% would be the residue, the waste product, of the original “pulping chemicals” and the lignin that has now been dissolved. That first liquid is called DMS (CH3 – S – CH3), but it quickly and easily further refined into DMSO.

DMSO is the main ingredient from which MSM is made by a controlled oxidation process using hydrogen peroxide (H2O2) and water. There are no other chemicals used, and the H2O2 is turned into water.

It is very important to realize that if you purchase MSM, then the MSM you receive has been distilled. NO CHEMICALS ARE LEFT BEHIND. It is the purest possible form of the chemical MSM and is made in one of the two factories in the USA.

DMSO by itself is a great health tool and it is also sold on this website.


This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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